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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ORC6L All Species: 23.64
Human Site: S120 Identified Species: 37.14
UniProt: Q9Y5N6 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5N6 NP_055136.1 252 28107 S120 M A S K I L K S Y E S S L P Q
Chimpanzee Pan troglodytes XP_001161833 252 28124 S120 M A S K I L K S Y E S S L P Q
Rhesus Macaque Macaca mulatta XP_001113625 252 28130 S120 M A S K I L K S Y E S S L P Q
Dog Lupus familis XP_539609 252 27646 S120 M A S K I L Q S Y K S S L P Q
Cat Felis silvestris
Mouse Mus musculus Q9WUJ8 262 29170 S120 L A A E I L Q S Y K S G L P E
Rat Rattus norvegicus NP_001028862 262 28796 S120 L A A G I L Q S Y E S S L P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521050 272 30470 R140 V A C K I L Q R Y E S S L P Q
Chicken Gallus gallus XP_414114 301 33273 R153 A A S E I L Q R Y E S S L P E
Frog Xenopus laevis NP_001086912 225 24746 R120 T A S E I L N R Y E S S L S Q
Zebra Danio Brachydanio rerio NP_997836 256 28612 R119 V A S Q I L Q R Y E T S L P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y1B2 257 29221 L120 K A E E L M T L F K G V A A T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793313 204 22972 I109 T I C K R Q K I K V D K T K L
Poplar Tree Populus trichocarpa XP_002316713 285 32005 L118 F V K K G L S L Y K D R F I A
Maize Zea mays NP_001151122 293 32508 L118 F V Q K G L S L Y K E R F L A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZVH3 284 31751 S118 S V Q N V L S S Y K E R F L A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.4 84.1 N.A. 74.4 70.6 N.A. 66.5 48.5 51.5 51.9 N.A. 26.4 N.A. N.A. 28.5
Protein Similarity: 100 99.2 98.8 90.8 N.A. 85.5 80.1 N.A. 74.6 61.7 65.8 71.4 N.A. 47 N.A. N.A. 45.6
P-Site Identity: 100 100 100 86.6 N.A. 53.3 66.6 N.A. 73.3 66.6 66.6 60 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 86.6 73.3 86.6 N.A. 40 N.A. N.A. 13.3
Percent
Protein Identity: 27.3 26.6 N.A. 25.3 N.A. N.A.
Protein Similarity: 47.3 47.4 N.A. 46.4 N.A. N.A.
P-Site Identity: 20 20 N.A. 20 N.A. N.A.
P-Site Similarity: 26.6 26.6 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 74 14 0 0 0 0 0 0 0 0 0 7 7 27 % A
% Cys: 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 % D
% Glu: 0 0 7 27 0 0 0 0 0 54 14 0 0 0 20 % E
% Phe: 14 0 0 0 0 0 0 0 7 0 0 0 20 0 0 % F
% Gly: 0 0 0 7 14 0 0 0 0 0 7 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 67 0 0 7 0 0 0 0 0 7 0 % I
% Lys: 7 0 7 54 0 0 27 0 7 40 0 7 0 7 0 % K
% Leu: 14 0 0 0 7 87 0 20 0 0 0 0 67 14 7 % L
% Met: 27 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 60 0 % P
% Gln: 0 0 14 7 0 7 40 0 0 0 0 0 0 0 40 % Q
% Arg: 0 0 0 0 7 0 0 27 0 0 0 20 0 0 0 % R
% Ser: 7 0 47 0 0 0 20 47 0 0 60 60 0 7 0 % S
% Thr: 14 0 0 0 0 0 7 0 0 0 7 0 7 0 7 % T
% Val: 14 20 0 0 7 0 0 0 0 7 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 87 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _